CrawlJobs Logo

Synthetics Lead Developer

barclays.co.uk Logo

Barclays

Location Icon

Location:
United Kingdom , London

Category Icon
Category:
IT - Software Development

Job Type Icon

Contract Type:
Not provided

Salary Icon

Salary:

Not provided
Save Job
Save Icon
Apply Position

Job Description:

Join Barclays as a Synthetics Lead Developer, where you will be responsible for supporting a global Synthetic & Financing platform that manages equity swaps and related derivative products. The platform is mission-critical, used globally across trading desks, and plays a central role in pre-trade processing, risk capture, pricing, and lifecycle management of equity swap transactions.

Job Responsibility:

  • Development and delivery of high-quality software solutions by using industry aligned programming languages, frameworks, and tools. Ensuring that code is scalable, maintainable, and optimized for performance
  • Cross-functional collaboration with product managers, designers, and other engineers to define software requirements, devise solution strategies, and ensure seamless integration and alignment with business objectives
  • Collaboration with peers, participate in code reviews, and promote a culture of code quality and knowledge sharing
  • Stay informed of industry technology trends and innovations and actively contribute to the organization’s technology communities to foster a culture of technical excellence and growth
  • Adherence to secure coding practices to mitigate vulnerabilities, protect sensitive data, and ensure secure software solutions
  • Implementation of effective unit testing practices to ensure proper code design, readability, and reliability

Requirements:

  • Mastery of microservices-based (Java stack), event-driven architectures, with the ability to design autonomous orchestration where services react to business events
  • Expertise in low-latency engineering and protocol selection, with the ability to choose and implement the right solution for the right job (e.g., REST for user operations, Kafka or Solace for workflows, RPC for internal data fetching)
  • Experience with distributed systems, including the ability to design and implement solutions where multiple service instances communicate while maintaining data integrity and managing concurrency

Nice to have:

  • Experience integrating deep observability (distributed tracing) into distributed, asynchronous systems
  • Experience in the Markets Prime Services domain, preferably with derivatives
  • Working knowledge of CI/CD pipelines
What we offer:
  • Competitive holiday allowance
  • Life assurance
  • Private medical care
  • Pension contribution

Additional Information:

Job Posted:
February 14, 2026

Employment Type:
Fulltime
Work Type:
Hybrid work
Icon
Barclays - All Job Offers
Job Link Share:
Copy Link Icon
Facebook Icon Twitter Icon LinkedIn Icon

Looking for more opportunities? Search for other job offers that match your skills and interests.

Briefcase Icon

Similar Jobs for Synthetics Lead Developer

Process Development Scientist

The Process Development Scientist at Amgen leads in the design, development, and...
Location
Location
Singapore , Tuas
Salary
Salary:
Not provided
amgen.com Logo
Amgen
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Doctorate degree OR Master’s degree and 2 years of directly related experience OR Bachelor’s degree and 4 years of directly related experience OR Diploma and 8 years of directly related experience
  • Strong knowledge of technologies and emerging scientific and regulatory directions for API processing is required
  • At least 6 years of relevant work experience in the commercial manufacturing environment within the biopharmaceutical industry is preferred
  • At least 4 years experience with regulated environments (i.e. cGMP) is preferred
  • Extensive knowledge of the manufacturing practices, regulatory requirements, scientific properties and risks associated with synthetic processing
  • Knowledge of different synthetic API processing platforms (i.e. reaction, concentration, crystallization, isolation, drying)
  • Experience in the development and qualification of methods used in release, in-process, and stability testing to analyze or to characterize synthetic molecule and product variants, and process-related impurities (e.g., HPLC, UPLC, mass spectrometry)
  • Setting up and running synthetic molecule laboratory-based experiment
  • Experience collaborating with experience networking and building solid working relationships across departments, with diverse and remote staff and with external collaborators
  • Team leadership, management, and facilitation skills
Job Responsibility
Job Responsibility
  • Lead in the design, development, and optimization of manufacturing processes
  • Apply scientific expertise to increase efficiency, improve product quality, and address manufacturing challenges, while maintaining adherence to regulatory standards
  • Be a Synthetic Chemistry subject matter expert
  • Provide scientific and technical direction to support commercial production of chemical synthetic drug substance
  • Support new product introduction, troubleshooting and improvement of existing and new API (synthetic molecule) processes
  • Assess initiatives associated to process improvements and optimizations
  • Develop and prepare laboratory-based experiments to support small scale model interrogation, investigations, and process improvements
  • Plan detailed procedures for defined projects, including timelines, milestones, methodological approaches, expected results and necessary resources
  • Support and/or lead cross-functional teams of experienced scientists and engineers through project challenges and implement advance scientific experiments
  • Support and/or lead process, process safety and material risk assessment performed on-site
What we offer
What we offer
  • Vast opportunities to learn and move up and across our global organization
  • Diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act
  • Generous Total Rewards Plan comprising health, finance and wealth, work/life balance, and career benefits
Read More
Arrow Right

Synthetic Prime - Product Development

Citi's Markets business is a global leader, providing a comprehensive suite of f...
Location
Location
United Kingdom , London
Salary
Salary:
Not provided
https://www.citi.com/ Logo
Citi
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Extensive experience in Prime Finance or Equity Finance, with a deep understanding of synthetic products such as portfolio swaps, hedge fund strategies across asset classes (equities, fixed income, derivatives), and market structure
  • Proven track record of successfully leading and delivering large-scale change initiatives and complex product development projects within a dynamic financial services environment
  • Exceptional communication skills, both written and oral, for effective stakeholder management, client engagement, and presenting strategic visions across all levels, including senior leadership
  • Strong analytical capabilities combined with a structured approach to problem-solving, strategic thinking, and the ability to define an end-state vision for complex financial platforms and products
  • Demonstrated ability to manage and lead virtual project teams within a matrix organizational structure, fostering collaboration and driving consensus among diverse groups of stakeholders
  • Bachelor's or Master's degree in Finance, Economics, Computer Science, or a related quantitative field, providing a solid foundation in financial markets and technology principles
Job Responsibility
Job Responsibility
  • Lead the strategic development and enhancement of Synthetic Prime Finance products and infrastructure, driving the end-to-end product lifecycle from conceptualization to market delivery
  • Define and articulate detailed business requirements (BRDs), create comprehensive project plans, and oversee the execution of global initiatives with a sharp focus on client needs and prevailing market trends
  • Collaborate extensively with sales, business managers, and technology teams to align product strategy with long-term business vision and integrate innovative solutions across the platform
  • Manage a book of work, ensuring efficient delivery, resource allocation, and prioritization of key strategic initiatives
  • Represent Citi in client engagements, actively gathering feedback and insights to champion continuous improvement in both the platform's capabilities and the overall client experience
  • Assess business priorities, identify strategic opportunities for growth and efficiency, and effectively communicate development plans, deliverables, and potential issues to all relevant stakeholders
What we offer
What we offer
  • 27 days annual leave (plus bank holidays)
  • A discretional annual performance related bonus
  • Private Medical Care & Life Insurance
  • Employee Assistance Program
  • Pension Plan
  • Paid Parental Leave
  • Special discounts for employees, family, and friends
  • Access to an array of learning and development resources
  • Fulltime
Read More
Arrow Right

Lead SRE

We have a 6 month contract to hire for a senior, hands-on Site Reliability Engin...
Location
Location
United States , St Louis
Salary
Salary:
Not provided
zeektek.com Logo
Zeektek
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Bachelor's degree
  • AWS Certified DevOps Engineer – Professional
  • Dynatrace Professional
  • One SaaS tool certifications (Prometheus Certified Associate (PCA), Datadog, New Relic)
  • 7+ years in SRE/Production Engineering/Platform roles
  • 2+ years leading initiatives or teams
  • Strong in Linux, networking fundamentals (HTTP, TLS, DNS, TCP), and distributed systems concepts
  • Proficiency with Go, Python, Shell Scripting, SQL, Java or JVM, JavaScript/TypeScript, YAML/HCL/JSON
  • Hands-on with IaC (Terraform) and CI/CD (GitLab CI, GitHub Actions, AWS/Azure DevOps)
  • Deep experience in AWS Cloud infrastructure
Job Responsibility
Job Responsibility
  • Lead SRE to drive reliability, scalability, observability (monitoring & alerts) and performance across the production platforms
  • Own the SLO/SLI strategy, modernize observability and incident response, and partner with application teams to deliver resilient systems
  • Define and govern SLOs/SLIs/Error Budgets for critical services
  • enforce guardrails and drive reliability roadmaps
  • Lead performance tuning collaboration with application teams to ensure high availability and low latency
  • Define and own infrastructure tuning to ensure scalability leading to high availability
  • Lead Metrics and automation driven Reliability
  • Dedug systems across layers
  • Architect and evolve CI/CD, infrastructure-as-code (IaC- Terraform)
  • Design and build serverless APIs (Lambda, API Gateway, SQS, SNS, DynamoDB, etc.)
What we offer
What we offer
  • Weekly Direct Deposit
  • 401K Matching
  • Competitive medical, dental and vision insurance
  • Consistent communication throughout your project
  • ZeekTek Referral Program
  • Fulltime
Read More
Arrow Right

Principal Scientist – Synthetic Separations

Amgen is seeking a highly motivated Senior Principal Scientist for their Discove...
Location
Location
India , Hyderabad
Salary
Salary:
Not provided
amgen.com Logo
Amgen
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Ph.D. in Chemistry, Analytical Chemistry, or related field with 8+ years of relevant experience, or M.S. with 12+ years of relevant experience in analytical or discovery chemistry within the biopharmaceutical industry
  • PhD in Analytical Chemistry or a related discipline with 8+ years of relevant industry experience in chromatographic analysis and/or purification of small molecules within a pharmaceutical R&D environment
  • Minimum of 5 years in a leadership or people management role
  • Develop, optimize, and implement analytical methods (LC, LC/MS, GC, SFC, NMR, HRMS, and related techniques) for purity assessment, structural confirmation, quantitative analysis, and reaction monitoring of synthetic compounds
  • Develop, optimize, and implement analytical methods (LC, LC/MS, GC, SFC, NMR, etc.) for purity assessment, structural confirmation, and reaction monitoring of synthetic compounds
  • Design, qualify, and maintain high-throughput or automated analytical workflows to support medicinal chemistry cycles
  • Collaborate with cross-functionally digital and automation groups to enable data-driven analytics and AI-supported structure prediction
  • Drive continuous improvement in analytical workflows and laboratory efficiency through process automation and robotics
  • Excellent written and verbal communication skills
  • Prepare concise, high-quality reports and presentations for internal review and external disclosure
Job Responsibility
Job Responsibility
  • Lead analytical strategy and execution for drug discovery-stage projects, enabling medicinal chemistry and early candidate selection through deep expertise in analytical and separation sciences
  • Bridge synthetic and analytical chemistry, ensuring rapid, reliable characterization of novel compounds and intermediates that drive Amgen’s small molecule discovery pipeline
  • Lead and manage the Synthetic Separations group, providing strategic direction, technical leadership, and mentorship to staff while prioritizing workloads, optimizing team performance, and serving as both a people manager and subject matter expert in synthetic separations
  • Design and qualify automated workflows enabling rapid turnaround and consistent data quality for purification and analysis of diverse compound libraries
  • Utilization of a diverse set of instruments and technologies, such as (but not limited to) HPLC, SFC, MS, mass-directed purification, and preparative-scale SFC and LC is necessary
  • Lead library purification efforts across multiple scales, ranging from microgram-level purification of screening compounds to hundreds of milligrams for advanced characterization
  • Assist in research efforts directed at improving process efficiencies, expanding the range of assays and applications, building state-of-the-art analytical capabilities, and improving technologies and infrastructure
Read More
Arrow Right

Lead Quality Assurance

Glean is looking for a talented Quality Assurance Lead to join our rapidly expan...
Location
Location
India , Bangalore
Salary
Salary:
Not provided
glean.com Logo
Glean
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • 6-9 years of software testing experience with strong focus on automation
  • Expert-level programming skills in Python or Java
  • Deep understanding of testing framework architecture (page objects, custom assertions, reporting integrations)
  • Strong experience with modern testing tools (Selenium, Playwright, Cypress etc) and API testing frameworks
  • Experience building CI/CD pipelines and working with Containers
  • Strong working knowledge of cloud platforms like AWS, GCP
  • Experience with performance testing tools and methodologies
  • Proven track record of building tools and frameworks used by engineering teams
  • Understanding of testing patterns and anti-patterns in automation
Job Responsibility
Job Responsibility
  • Lead the development of our test automation frameworks, focusing on reliability, maintainability, and speed
  • Create reusable test libraries and components that can be shared across different product areas
  • Lead technical implementation of performance testing and monitoring solutions
  • Develop custom reporting and analytics tools to provide insights into test coverage and quality metrics
  • Drive adoption of newer testing technologies and approaches (visual testing, accessibility, security, AI-assisted testing, etc.)
  • Provide technical mentorship to QA engineers on automation best practices and framework usage
  • Optimize test execution pipelines for faster feedback in CI/CD environments
  • Implement solutions for test data management and synthetic data generation
  • Partner with development teams to implement shift-left testing practices
  • Lead root cause analysis for critical issues and drive systematic improvements to prevent recurrence
Read More
Arrow Right

Senior Director, Drug Substance Development and Manufacturing (Peptide)

We are seeking an accomplished and strategic Senior Director, Drug Substance Dev...
Location
Location
United States , Waltham
Salary
Salary:
210000.00 - 270000.00 USD / Year
kailera.com Logo
Kailera Therapeutics
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Minimum of 10+ years of progressive, relevant experience in drug substance development and manufacturing
  • Deep expertise in both synthetic and recombinant manufacturing approaches
  • Hands-on experience with the synthesis and manufacturing of peptides is mandatory
  • Demonstrated track record in managing clinical-scale supply, process characterization and optimization, technical transfers, and process validation activities
  • Sound technical skills in applying scientific principles to complex process design, implementation, and successful technology transfer
  • Solid knowledge of current Good Manufacturing Practices (cGMPs), Quality systems, and global regulatory requirements (e.g., FDA, EMA)
  • Proven experience with the drafting, review, and authoring of CMC sections for major global regulatory submissions (e.g., IND, NDA, MAA)
  • Exceptional solution-based critical thinking skills and the ability to operate with a keen sense of urgency and an entrepreneurial spirit
  • Demonstrated ability to ensure accountability of self and others, coupled with strong detail-orientation
  • Ability to strategically contribute to and manage multiple concurrent projects
Job Responsibility
Job Responsibility
  • Direct and lead all process development, scale-up, technology transfer, and validation activities for peptide drug substance manufacturing across all Contract Development and Manufacturing Organizations (CDMOs)
  • Establish and drive continuous improvement initiatives focused on enhancing manufacturing efficiency, enabling cost reduction, and establishing strategic redundancies across the CDMO network
  • Define the long-term vision for manufacturing by maintaining a deep knowledge of industry trends, technological advancements, green manufacturing processes, and emerging regulatory changes
  • Manage and enforce CDMO performance against key project timelines, deliverables, and costs
  • Lead the negotiation and execution of complex technical agreements and work orders with CDMO partners
  • Oversee budget planning and forecasting for all outsourced drug substance manufacturing activities
  • Serve as the strategic lead for drug substance activities, driving seamless collaboration across Analytical Development, Formulation, Quality Assurance, and Regulatory Affairs
  • Oversee the preparation and completion of drug substance modules (e.g., Module 3) for all regulatory dossiers (e.g., IND, NDA)
  • Direct the preparation and final authorship of high-quality technical reports, executive summaries, and presentations to effectively communicate results and progress to internal leadership and external stakeholders
What we offer
What we offer
  • Comprehensive health coverage
  • Flexible time off
  • Paid holidays
  • Year-end shutdown
  • Monthly wellness stipend
  • Generous 401(k) match
  • Tuition reimbursement
  • Commuter benefits
  • Disability and life insurance
  • Annual bonus opportunities
  • Fulltime
Read More
Arrow Right

Senior Data Scientist

We’re looking for a experienced Data Scientist with deep learning experience to ...
Location
Location
France , Lyon
Salary
Salary:
Not provided
hawkcell.com Logo
HawkCell
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • 4+ years of experience in deep learning applied to imaging
  • Proven track record of bringing models to production
  • Strong coding standards and experience with Git/GitHub collaboration tools
  • Proficiency in packaging tools like Poetry or uv
  • Published research papers and eagerness to continue publishing
  • Comfortable working in a fast-paced, collaborative environment
  • Ability to work in an international and English-first environment
Job Responsibility
Job Responsibility
  • Lead development of models for denoising, synthetic contrast generation, and classification
  • Design algorithms for segmentation, localization, and characterization of pathologies
  • Collaborate with other DS team members and mentor junior profiles
  • Ensure clean, maintainable code and scalable model packaging (Poetry/uv)
  • Put models into production and help design robust evaluation pipelines
  • Publish your work in peer-reviewed venues and represent Hawkcell in the AI community
  • Contribute to IT topics and help bridge R&D and productionization
What we offer
What we offer
  • A mission to revolutionize the animal healthcare industry
  • A great and ambitious team to grow with
  • An international culture with 10+ nationalities in the team
  • An amazing office for you to share with other Hawkstars in Lyon, France
Read More
Arrow Right

Dynatrace Consultant

The Dynatrace Consultant will work on application observability in Hybrid Cloud ...
Location
Location
India , Noida
Salary
Salary:
Not provided
https://www.soprasteria.com Logo
Sopra Steria
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Enable observability of applications in Hybrid Cloud
  • configure application monitoring, anomaly and alert profiles, synthetic monitoring, log monitoring
  • understand transaction processing, multi-tier application development, web infrastructure
  • define and lead corrective actions for application issues
  • understand security issues, customer processes
  • support Root Cause Analysis identification
  • work in a 24/7 environment
  • understand DQL queries
  • familiarity with API and integration
  • experience with Cloud platforms (Azure/AWS/GCP)
Job Responsibility
Job Responsibility
  • Enable observability of applications
  • configure monitoring tools
  • frame observability objectives with customer business and IT teams
  • act as in charge of technical solutions
  • perform monitoring and metrics analysis
  • handle security and change processes
  • assist with Root Cause Analysis
  • utilize DQL queries
  • integrate APIs
  • work in collaboration with Cloud platforms and network systems.
What we offer
What we offer
  • Inclusive and respectful work environment
  • opportunities for people with disabilities
  • Fulltime
Read More
Arrow Right
Jobs by Category
Art and Entertainment Jobs Banking Jobs Call Center Jobs Construction Jobs Consulting Jobs Customer Service Jobs Education Jobs Energy Jobs Finance Jobs Gastronomy Jobs Health and Beauty Jobs Hospitality and Tourism Jobs Human Resources Jobs Insurance Jobs IT - Administration Jobs IT - Software Development Jobs Legal Jobs Logistics Jobs Manufacturing Jobs Marketing, Digital Marketing, SEO, SEM Jobs Media Jobs Nursing Jobs Office Administration Jobs Pharmacy Jobs Physical Work Jobs Public Relations Jobs Public Sector Jobs Purchasing Jobs Quality Control Jobs Real Estate Jobs Research and Development Jobs Sales Jobs
Job Positions Jobs by Country
United States Jobs United Kingdom Jobs India Jobs Canada Jobs Australia Jobs Germany Jobs Ireland Jobs Poland Jobs
Company
Blog About Us Contact
Follow Us
Facebook
X (Twitter)
LinkedIn
Instagram
CrawlJobs Group
ITFlashcards AllDevBlogs
© 2026 CrawlJobs Ltd. All Rights Reserved
Terms & Conditions Privacy Policy