CrawlJobs Logo

Senior Director, Technical Operations

loyal.com Logo

Loyal

Location Icon

Location:
United States

Category Icon
Category:
Research and Development

Job Type Icon

Contract Type:
Not provided

Salary Icon

Salary:

230000.00 - 280000.00 USD / Year
Save Job
Save Icon
Apply Position

Job Description:

We’re seeking an experienced Senior Director, Technical Operations to provide technical leadership across all CMC disciplines as we advance our programs from early development through commercialization — including preparations for upcoming product launch. This role serves as a cornerstone of our Technical Operations organization, ensuring connectivity, scientific rigor, and technical excellence across process, analytical, and formulation development, manufacturing, and supply.

Job Responsibility:

  • Provide technical leadership and integration across process, analytical, and formulation development, ensuring scientific rigor, data integrity, and seamless progression from early development through commercialization
  • Drive technical connectivity among CMC functions to maintain alignment, consistency, and robust science across all development stages
  • Lead technical risk assessment, mitigation, and decision-making, ensuring issues are identified, analyzed, and resolved through data-driven approaches
  • Partner with CMC functional leads and CDMOs to develop and refine scalable, robust, and reproducible processes for drug substance and oral solid dosage drug and finished products
  • Oversee technical readiness for key milestones including IND/IMPD, NDA/MAA, and commercial launch
  • Lead or contribute to CMC sections of regulatory submissions and represent Loyal in technical discussions with regulatory authorities
  • Collaborate closely with Quality, Regulatory, Clinical, and Commercial functions to ensure technical and operational alignment
  • Mentor and guide internal scientists and external partners to uphold a culture of technical excellence and accountability

Requirements:

  • PhD in Chemical Engineering or a closely related discipline, or equivalent industrial experience with deep technical expertise in process, analytical, and formulation development
  • 12+ years of experience in biopharmaceutical CMC development and manufacturing, with increasing technical leadership responsibilities
  • Proven experience leading early CMC development through successful product launch, including process validation and technology transfer
  • Experience with small molecules and oral solid dosage forms strongly preferred
  • Strong understanding of process and formulation design, scale-up, and control for both drug substance and drug product
  • Demonstrated success guiding CDMOs and cross-functional CMC teams through complex technical challenges
  • Comprehensive knowledge of global CMC regulatory expectations (FDA, EMA, ICH) and ability to translate technical findings into regulatory strategies
  • Excellent technical judgment with the ability to synthesize complex data into clear, sound decisions
  • Collaborative, pragmatic, and thrives in a fast-paced, matrixed, mission-driven biotech environment

Nice to have:

  • Experience building or scaling Technical Operations capabilities during the transition from development to commercialization
  • Familiarity with lifecycle management, continued process verification, and commercial supply optimization
  • Experience with veterinary or animal health manufacturing
  • Passion for Loyal’s mission to bring science-driven longevity therapeutics to dogs
What we offer:
  • Full-coverage health insurance — medical, dental and vision — for you and your dependents
  • $1,000 home office equipment stipend
  • $1,200/year learning budget for books, courses, etc.
  • $250/month wellness budget for gym, cleaners, spa, food, etc.
  • All 3-day weekends are turned into 4-day weekends
  • Unlimited vacation and paid holidays
  • Paw-ternity leave — adopt a dog and get a day off with your new family member
  • Competitive salary
  • Company equity options grant for new hires

Additional Information:

Job Posted:
December 10, 2025

Employment Type:
Fulltime
Work Type:
Remote work
Icon
View All Jobs In This Company
Job Link Share:
Copy Link Icon
Facebook Icon Twitter Icon LinkedIn Icon

Looking for more opportunities? Search for other job offers that match your skills and interests.

Briefcase Icon

Similar Jobs for Senior Director, Technical Operations

Senior Director of Corporate IT

Senior Director of Corporate IT (End User Services/AI, Systems Engineering, and ...
Location
Location
United States , San Francisco
Salary
Salary:
180000.00 - 304000.00 USD / Year
https://www.pagerduty.com Logo
PagerDuty
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • 8+ years of experience working in IT operations, overseeing large information technology projects
  • 6+ years of people management experience leading multiple technical teams, distributed across multiple geographies
  • Proven experience in operating and managing security, automation technology, and automation programs
  • Excellent understanding of computer systems, security, network and systems administration, databases and data storage systems, and telecommunications systems
  • Experience with agile and scrum methodologies
  • Bachelor's degree in computer science (or a related field) or equivalent work experience
  • Experience working within high-growth, cloud-first (AWS), B2B SaaS companies
  • Excellent leadership, decision-making, and project management skills
  • Excellent communication and influencing skills
  • Experience with Okta, Google Workspace, Slack, Jamf, Microsoft 365, Atlassian Cloud, Jira, Oomnitza, automation tools, AWS, and Zoom
Job Responsibility
Job Responsibility
  • Provide technology vision and leadership for deploying IT initiatives that improve collaboration, cost-effectiveness, compliance, and security at enterprise scale
  • Architect and scale IT Operations and Infrastructure to support a growing, hybrid workforce, ensuring high availability and performance of critical systems
  • Drive the strategy, implementation, and adoption of enterprise employee-facing AI programs and automation, enhancing productivity and user experience across the organization
  • Partner closely with the CISO organization to design, deploy, and operate robust IT security solutions, ensuring the protection of corporate infrastructure and data
  • Manage vendor relationships and identify opportunities to optimize costs through efficient internal operations, rationalized investments, and business enablement
  • Consult with senior-level stakeholders across the organization to identify business and technology needs, translating them into actionable IT strategies
  • Oversee ticket escalation and ensure that service level agreements (SLAs) and defined metrics are consistently met or exceeded
  • Ensure employees receive professional, efficient, and effective support, with a focus on continuous improvement and user satisfaction
  • Monitor and optimize the delivery and operation of IT services, proactively identifying and resolving issues to maintain seamless business operations
  • Provide regular metrics and KPIs across functions to gauge the effectiveness of service delivery and inform strategic decisions
What we offer
What we offer
  • Comprehensive benefits package from day one
  • Flexible work arrangements
  • Company equity
  • ESPP (Employee Stock Purchase Program)
  • Retirement or pension plan
  • Generous paid vacation time
  • Paid holidays and sick leave
  • Dutonian Wellness Days & HibernationDuty - companywide paid days off in addition to PTO
  • Paid parental leave: 22 weeks for pregnant parent, 12 weeks for non-pregnant parent
  • Paid volunteer time off: 20 hours per year
  • Fulltime
Read More
Arrow Right

Senior Art Director

Seeking an Art Director with creative passion. You must have a fine eye for deta...
Location
Location
United States , Stuart
Salary
Salary:
Not provided
cottonco.com Logo
Cotton & Company
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • 3+ years design experience in an agency setting is required
  • Must possess exceptional computer skills
  • Macintosh operating platform a must
  • Thorough knowledge of the following software applications is required, InDesign, Adobe Illustrator, scanning software, Adobe Photoshop and any widely utilized word processing application
  • Mastered composition techniques (multiple elements and interactive pieces) in producing polished final pieces
  • Attention to detail
  • Comprehensive photo-retouching and image editing skills
  • Strong Adobe Creative Cloud suite experience
  • Demonstrated ability to think creatively and provide marketable solutions in conceiving, developing, and producing tactics
  • A team player
Job Responsibility
Job Responsibility
  • Designs Logos, print ads, brochures, booklets, fliers, TV commercials, billboards, interactive/web ads and more
  • Meets as needed with account executives and design/production personnel to ensure coordination between traditional and interactive advertising and marketing efforts
  • Works with other art directors, copywriters and additional designated “team” personnel in production of said materials
  • Works with production personnel, providing complete input and any instruction and supervision required to smoothly complete production of approved design
  • Provides all required specifications (colors, fonts, papers, sizes, etc.) to production department
  • Reviews all production materials on assigned projects and signs off prior to forwarding job to account executive and CMO for further required approvals/outside production
  • Art directs videos, photo shoots, audio tapings, press-proofing, etc. and supervises freelancers assigned to art director’s projects as requested by traffic manager
  • Ability to multi-task, prioritize and work well under pressure is a must
  • Meets with account executives/traffic manager as required ensuring timely, accurate completion of assigned projects
  • Keeps senior art director/creative director informed of need to upgrade design-related computer hardware/software
Read More
Arrow Right

Senior Director, Professional Services

Senior leadership role heading the Professional Services team at PagerDuty, resp...
Location
Location
United States , San Francisco
Salary
Salary:
180000.00 - 275000.00 USD / Year
https://www.pagerduty.com Logo
PagerDuty
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Proven experience (10+ years) in professional services, consulting, or a related field
  • At least 5 years in a senior leadership role
  • Demonstrated success in building and scaling delivery methodologies for complex, multi-phase projects
  • Strong understanding of project management frameworks (e.g., Agile, Waterfall, hybrid approaches)
  • Experience designing delivery models that support and enable senior-level consultants
  • Exceptional leadership, communication, and stakeholder management skills
  • Ability to thrive in a fast-paced, high-growth environment
  • Bachelor's degree required
  • Advanced degree or relevant certifications (PMP, Six Sigma, etc.) a plus
Job Responsibility
Job Responsibility
  • Develop and own delivery methodology
  • Scale delivery to support senior consultants
  • Team leadership of project managers, consultants, and technical experts
  • Customer engagement for enterprise customers
  • Establish and track key performance indicators (KPIs)
  • Stakeholder collaboration with Sales, Product, Customer Success, and Support
  • Thought leadership and industry representation
What we offer
What we offer
  • Comprehensive benefits package from day one
  • Flexible work arrangements
  • Company equity
  • ESPP (Employee Stock Purchase Program)
  • Retirement or pension plan
  • Generous paid vacation time
  • Paid holidays and sick leave
  • Dutonian Wellness Days & HibernationDuty
  • Paid parental leave: 22 weeks for pregnant parent, 12 weeks for non-pregnant parent
  • Paid volunteer time off: 20 hours per year
  • Fulltime
Read More
Arrow Right

Senior Director, Application Development, China

Accountable for the development and delivery of innovative and high-quality cust...
Location
Location
China , Shanghai
Salary
Salary:
Not provided
https://www.marriott.com Logo
Marriott Bonvoy
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • 10+ years of application development leadership experience with a minimum of 3 years at a Senior Director level or 6 years at Director level
  • Direct experience leading technology teams in defining, creating and supporting enterprise-scale solutions with strong knowledge of industry-standard Web/Mobile/WeChat technologies and Chinese Digital eco-systems like Tencent and Alibaba etc.
  • Strong knowledge of general industry trends, technologies and platforms
  • Demonstrated experience in Agile development methodologies, specifically with large-scale initiatives and geographically distributed teams
  • Direct management of cross functional, sourced, or matrixed teams
  • Five year’s recent experience with architectural frameworks and the various approaches to the Systems Development Life Cycle (SDLC)
  • Experience working with consulting companies to lead the technology solution, application development, and production operations for $10M+ of efforts
  • Deep Experience in building highly scalable and secure modern Digital platform architectures for web platforms
  • Experience in building headless and headful solutions, with modern UI stack with Java, Node.JS, React, Vue and Redux and CMS and Experience
  • Experience in building architecture and solution for iOS App, Android App, WeChat Mini Program and WeChat Ecosystem
Job Responsibility
Job Responsibility
  • Accountable for the development and delivery of innovative and high-quality customer-facing digital experiences for China and drives the growth and guest satisfaction of Marriott’s Digital channels
  • Follows and provides input to standard application development tools and processes to promote project quality for client-facing systems
  • Manages day-to-day relationships with global information technology teams and partners with local and global discipline stakeholders to deliver best in class experiences
  • Implements and manages continuous improvement programs to improve quality, consistency, and client satisfaction
  • Works with the Architecture and Development lead to facilitate consistency of service delivery across client groups
  • Builds and maintains a standard set of application development tools and processes that will drive consistency and predictability throughout the SDLC for all client groups including: SDLC standard tools and processes for both waterfall and agile development, Estimating standard tools and processes, incorporating flexibility for small and large projects, Deployment standard tools and processes
  • Monitors projects for adherence to defined application development processes
  • Works with IT organization to create broader IT related and corporate standards and policies where necessary
  • Communicates important application development policy changes that affect service provider and/or Marriott operations
  • Manages application development projects in partnership with IT teams, business partners and providers
What we offer
What we offer
  • Equal opportunity employer
  • Hiring a diverse workforce and sustaining an inclusive, people-first culture
  • Non-discrimination on any protected basis, such as disability and veteran status, or any other basis covered under applicable law
  • More brands, more hotels and more opportunities for associates to grow and succeed
  • Fulltime
Read More
Arrow Right
New

Senior Director, Manufacturing, Science & Technology

As a Senior Director, Manufacturing, Science & Technology, you will lead a high-...
Location
Location
United Kingdom , London
Salary
Salary:
Not provided
theramex.com Logo
Theramex
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • PhD in Chemistry, Biochemical Engineering, or a related scientific discipline
  • Extensive experience in pharmaceutical or biotechnology manufacturing, with deep expertise in process development for both small and large molecules
  • Proven knowledge in sterile processing, fill-finish operations, and packaging
  • Strong understanding of CMC requirements and regulatory dossier submissions (EMA, FDA)
  • Inspirational leadership with a hands-on approach to managing technical operations, complex projects, and cross-functional teams
  • Exceptional analytical, scientific, and communication skills, with the ability to convey complex concepts to diverse stakeholders
  • Fluency in English is essential
  • Willingness to travel internationally as required
Job Responsibility
Job Responsibility
  • Provide strategic direction and technical oversight for all external manufacturing activities
  • Lead and oversee the execution of technology transfers, validation programs, and lifecycle management for both new and existing products
  • Establish and monitor performance metrics, proactively manage risks, and make data-driven decisions aligned with business objectives
  • Ensure robust technical evaluations for material changes, process scale adjustments, and cost-efficiency initiatives
  • Contribute to vendor qualification, audit processes, and long-term capacity and supply planning
  • Ensure full compliance with cGMP regulations and internal quality standards across all operations
  • Lead and manage a team of pharmaceutical technical and scientific experts
  • Serve as the primary technical liaison with CMOs, ensuring alignment with strategic goals and regulatory expectations
What we offer
What we offer
  • A fast-paced environment, with broad exposure, where you can develop professionally – even outside your area of expertise
  • We support you as you grow and learn, and we love to celebrate success and recognize performance
  • We provide opportunities for driven and talented professionals who want to be part of our exciting journey
Read More
Arrow Right

Senior Director of Engineering, Infrastructure

Senior Director of Engineering role leading the Infrastructure group at PagerDut...
Location
Location
United States , San Francisco
Salary
Salary:
233000.00 - 392000.00 USD / Year
https://www.pagerduty.com Logo
PagerDuty
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Proven experience in senior engineering leadership roles, managing multiple layers of managers
  • Significant experience as a hands-on technical contributor earlier in your career
  • Deep knowledge of modern infrastructure and software delivery: high availability, distributed systems, public cloud (AWS), microservices, containers, CI/CD pipelines, observability, and automation
  • Track record of building and scaling high-performing, inclusive engineering organizations
Job Responsibility
Job Responsibility
  • Define and drive the multi-year strategy for PagerDuty's infrastructure and platform foundations
  • Strong ownership of PagerDuty's reliability patterns and practices
  • Bar raiser for all engineering functions
  • Lead, mentor, and scale a diverse team of Engineering Managers, Senior Managers, and technical leaders across multiple geographies
  • Ensure the reliability, scalability, and security of PagerDuty's global SaaS platform
  • Partner with peers in Engineering, Product, and Security to deliver large cross-functional initiatives
  • Champion engineering excellence: CI/CD maturity, observability best practices, operational rigor, and incident readiness
  • Manage budgets, headcount, and vendor relationships to optimize infrastructure investments
  • Represent Infrastructure externally with customers and partners, and internally with executives, as a trusted voice on technical and business tradeoffs
  • Foster a culture of inclusion, accountability, collaboration, and growth
What we offer
What we offer
  • Competitive salary
  • Comprehensive benefits package
  • Flexible work arrangements
  • Company equity
  • ESPP (Employee Stock Purchase Program)
  • Retirement or pension plan
  • Generous paid vacation time
  • Paid holidays and sick leave
  • Dutonian Wellness Days & HibernationDuty - companywide paid days off in addition to PTO
  • Paid parental leave: 22 weeks for pregnant parent, 12 weeks for non-pregnant parent
  • Fulltime
Read More
Arrow Right

Senior Director of Engineering, Infrastructure

Senior Director of Engineering to lead the Infrastructure group at PagerDuty, se...
Location
Location
United States , Atlanta
Salary
Salary:
233000.00 - 392000.00 USD / Year
https://www.pagerduty.com Logo
PagerDuty
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Proven experience in senior engineering leadership roles, managing multiple layers of managers
  • Significant experience as a hands-on technical contributor earlier in your career
  • Deep knowledge of modern infrastructure and software delivery: high availability, distributed systems, public cloud (AWS), microservices, containers, CI/CD pipelines, observability, and automation
  • Track record of building and scaling high-performing, inclusive engineering organizations
Job Responsibility
Job Responsibility
  • Define and drive the multi-year strategy for PagerDuty's infrastructure and platform foundations
  • Strong ownership of PagerDuty's reliability patterns and practices
  • Lead, mentor, and scale a diverse team of Engineering Managers, Senior Managers, and technical leaders across multiple geographies
  • Ensure the reliability, scalability, and security of PagerDuty's global SaaS platform
  • Partner with peers in Engineering, Product, and Security to deliver large cross-functional initiatives
  • Champion engineering excellence: CI/CD maturity, observability best practices, operational rigor, and incident readiness
  • Manage budgets, headcount, and vendor relationships to optimize infrastructure investments
  • Represent Infrastructure externally with customers and partners, and internally with executives
  • Foster a culture of inclusion, accountability, collaboration, and growth
What we offer
What we offer
  • Comprehensive benefits package
  • Flexible work arrangements
  • Company equity
  • ESPP (Employee Stock Purchase Program)
  • Retirement or pension plan
  • Generous paid vacation time
  • Paid holidays and sick leave
  • Dutonian Wellness Days & HibernationDuty - companywide paid days off in addition to PTO
  • Paid parental leave: 22 weeks for pregnant parent, 12 weeks for non-pregnant parent
  • Paid volunteer time off: 20 hours per year
  • Fulltime
Read More
Arrow Right

Senior Director of Product Management

The goTenna Product team is seeking a highly professional and experienced Produc...
Location
Location
Salary
Salary:
175000.00 - 220000.00 USD / Year
gotenna.com Logo
goTenna
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • 6+ years of experience working as Director of Product Management, Product Lifecycle Manager or Product Portfolio Manager in a technical product field - preferably in the telecoms, LMR radio or satellite systems segments
  • 4+ years of experience with Agile methodologies for Software Development (including use of Jira & Confluence)
  • 3+ years of experience with Waterfall/Stage-Gate methodologies for Hardware Development processes
  • Demonstrated experience managing business initiatives involving a portfolio of products in various lifecycle stages
  • Experience conducting market research, technical research and competitive analysis
  • Professional Communication skills: project specifications, documentation and presentations
  • Experience directly managing Product Managers and/or Product Owners
  • ITAR: U.S. Citizen or Green Card Required
Job Responsibility
Job Responsibility
  • Strategic Product Leadership: The Senior Director of Product Management is the key owner of an assigned product or product portfolio
  • Portfolio Strategy: Working in conjunction with the VP of Product and key internal and external stakeholders, the Product Manager shall define and communicate a compelling, long-term product strategy that aligns with market opportunities, customer needs and overall business objectives
  • Market & Competitive Analysis: Conduct deep market research, including regular interaction with current lighthouse customers, target market customers, industry experts, and sales channels
  • Business Case Development: Develop and maintain robust business cases for new product investments, justifying resource allocation, forecasting financial returns (ROI), and defining success metrics
  • Go-to-Market Strategy: Partner with Marketing, Sales, and Business Development to define and execute effective go-to-market plans for product launches
  • Customer & Stakeholder Empathy: Serve as the primary voice of the customer, translating complex operational requirements from critical communications end-users into actionable product requirements
  • Roadmap Management: Own, prioritize, and maintain the product roadmap for the product or product portfolio
  • Requirements Definition: Create clear, concise, and prioritized Product Requirements Documents (PRDs), translating those requirements into initiatives and feature epics
  • Feature Prioritization: Use data-driven decisions, product strategic goals, and market feedback to make tough, objective decisions on feature trade-offs and backlog prioritization
  • Lifecycle Management: Manage products across their entire lifecycle, including defining end-of-life strategies and transition plans for legacy systems
What we offer
What we offer
  • Equity
  • 401(k) plan
  • Unlimited PTO
  • Parental Leave with Pay
  • Holiday pay (including December recess)
  • Medical, Dental, Vision and life insurance
  • Pre-tax benefits
  • Short- and Long-term disability plans
  • Professional Development Stipend
  • Fulltime
Read More
Arrow Right
Welcome to CrawlJobs.com –
Your Global Job Discovery Platform
At CrawlJobs.com, we simplify finding your next career opportunity by bringing job listings directly to you from all corners of the web. Using cutting-edge AI and web-crawling technologies, we gather and curate job offers from various sources across the globe, ensuring you have access to the most up-to-date job listings in one place.
Jobs by Category
Art and Entertainment Jobs Banking Jobs Call Center Jobs Construction Jobs Consulting Jobs Customer Service Jobs Education Jobs Energy Jobs Finance Jobs Gastronomy Jobs Health and Beauty Jobs Hospitality and Tourism Jobs Human Resources Jobs Insurance Jobs IT - Administration Jobs IT - Software Development Jobs Legal Jobs Logistics Jobs Manufacturing Jobs Marketing, Digital Marketing, SEO, SEM Jobs Media Jobs Nursing Jobs Office Administration Jobs Pharmacy Jobs Physical Work Jobs Public Relations Jobs Public Sector Jobs Purchasing Jobs Quality Control Jobs Real Estate Jobs Research and Development Jobs Sales Jobs
Job Positions Jobs by Country
United States Jobs United Kingdom Jobs India Jobs Australia Jobs Canada Jobs Poland Jobs Ireland Jobs Spain Jobs
Company
Blog About Us Contact
Follow Us
Facebook
X (Twitter)
LinkedIn
Instagram
© 2025 CrawlJobs Ltd. All Rights Reserved
Terms & Conditions Privacy Policy