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We’re looking for a motivated Research Scientist to join the laboratory of Dr Lizbeth Sayavedra in the Food, Microbiome and Health programme at Quadram Institute Bioscience. The postholder will help investigate how microbial sulfur and nitrogen metabolism influences human health, with a particular focus on protein malnutrition and obesity. Research in the lab centres on sulphate- and sulphite-reducing bacteria of the Desulfovibrionaceae and their interactions with the host and the wider gut microbiome. Our work uses a range of advanced host-relevant experimental systems, including in vitro and in vivo models, integrated with anaerobic microbiology and metagenomics.
Job Responsibility:
Designing and performing tissue culture, organoid, or in vivo experiments to investigate host–microbiome interactions
Coordinating microbial perturbation experiments linked to dietary or metabolic interventions
Anaerobic culturing and preparation of gut bacteria, particularly members of the Desulfovibrionaceae, for host interaction studies
Application of genetic and functional genomics approaches to investigate sulfur and nitrogen metabolic pathways
Integration of host experimental data with metagenomic analyses, including interpretation of microbial functional potential and activity
Contribution to study design, data integration, publications, presentations, and future grant proposals
Requirements:
PhD in microbiology, molecular microbiology or a related discipline
Demonstrable hands-on experience with tissue culture, organoids, and/or in vivo models
Solid understanding of host–microbiome interactions and experimental design in host systems
Working knowledge of metagenomics and bioinformatics sufficient to analyse or interpret complex datasets
Ability to work independently and integrate results across host and microbial systems
Nice to have:
Experience working with anaerobic bacteria or complex microbial communities
Familiarity with Linux-based environments or reproducible data analysis workflows
What we offer:
Possibility for contract extension
Commitment to development of staff
Family, faith and diversity friendly working arrangements