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We are seeking an experienced Molecular Biologist to join the Core Technologies team and collaborate with scientists across the organization. Core Technologies implements scientific tools and molecular techniques to solve biological research problems, with a particular focus on mapping genotype phenotype relationships. In this role, you’ll spearhead our efforts in mutagenesis, polymorphism targeted sequencing, and molecular phenotype identification. You will lead molecular assay development, translating pilot projects into robust systems accessible across the company. Our evolutionary perspective spans the tree of life, and you’ll help drive this vision by designing experiments and developing protocols tailored to diverse, non-traditional, model organisms. You’ll design and optimize novel molecular workflows to interrogate genotype–phenotype relationships, with a focus on developing NGS-based assays beyond traditional short-read sequencing. More broadly, you’ll serve as a molecular biology expert, guiding decision-making and ensuring scientific rigor across experimental efforts.
Job Responsibility:
Design and execute protocols for mutagenesis and targeted sequencing of polymorphisms across a broad range of unicellular and multicellular organisms
Develop and implement quantitative and qualitative molecular assays to enable screening and functional characterization of diverse molecular phenotypes
Ensure quality of resulting datasets is appropriate for downstream applications and assays and processes are well documented and parameterized
Independently troubleshoot challenges, such as comparing orthologous techniques for capturing relevant genotypic data at higher throughput and lower cost
Prepare RNA and DNA libraries for sequencing
Automate or develop higher throughput strategies for recurring molecular biology workflows
Project manage contract work with outside consultants, CROs, and sequencing vendors
Manage and guide team performance and provide professional and technical mentorship
Keep detailed experimental records and documentation (SOPs) for all workflows
Synthesize ideas, data, and findings into fully open-access pubs and engage with the scientific community to maximize impact and garner feedback that improves the work
Requirements:
Ph.D. or equivalent experience in Molecular Biology or Biochemistry
At least 3 years of full-time relevant scientific experience post-PhD, including leadership roles
Hands-on technical experience in the following areas: mutagenesis, NGS method development, and library prep optimization
Experience building and optimizing computational pipelines to analyze NGS experiments
Passionate about Tidy Data and bioinformatic workflows that follow best software development practices
Effective project management ability demonstrated by ability to scope work with key stakeholders, create milestones and timelines, identify blockers
Ability to align team with cross-functional goals and organize effective collaborations
An excellent verbal and written science communicator for both general and technical audiences
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