CrawlJobs Logo

Computational Biology Lead

bioptimus.com Logo

Bioptimus

Location Icon

Location:
France , Paris

Category Icon
Category:
Research and Development

Job Type Icon

Contract Type:
Not provided

Salary Icon

Salary:

Not provided
Save Job
Save Icon
Job offer has expired

Job Description:

Bioptimus is building the first universal AI foundation model for biology to fuel breakthrough discoveries and accelerate innovation in biomedicine. We are seeking an experienced computational biology leader to guide the evaluation and real-world applications of our foundation models. You will bring your expertise in biology and data science to provide crucial scientific direction, ensuring we tackle the most important problems in drug development and translational research. This is a senior individual contributor role within our R&D team that will expand into management as the company grows.

Job Responsibility:

  • Identify and develop AI and foundation model approaches to answer key questions in biopharma and translational research
  • Collaborate with our research team to identify, acquire, or generate new datasets and data modalities to incorporate into our models
  • Contribute to publications, patents, and case studies showcasing novel applications in pharma R&D
  • Represent Bioptimus at conferences, workshops, and client meetings, demonstrating domain expertise and the potential of AI-driven drug development
  • Mentor junior team members and provide domain expertise to our R&D team
  • Translate biopharma research questions into actionable machine learning objectives and tasks
  • Work closely with product, business, and research teams to define feature priorities
  • Serve as a trusted scientific partner during external technical discussions
  • Design proof-of-concept studies, address domain-specific queries, and deliver high-quality presentations that highlight the value of Bioptimus' solutions
  • Provide ongoing training and support to partners on how to interpret and apply our foundation models in R&D pipelines
  • Help unlock actionable insights in transcriptomics, proteomics, histology, and beyond

Requirements:

  • PhD or equivalent experience in Computational Biology, Bioinformatics, or related field
  • 4+ years professional experience in Biopharma R&D
  • Deep understanding of biopharma R&D use-cases, challenges, tools and processes
  • Ability to break down high-level biopharma use-cases into actionable recommendations for the research & product team
  • Extensive experience working with end-to-end genomics and multi-omics datasets (transcriptomics, single-cell, proteomics, imaging, etc..), from dataset generation & QC, to the analysis and interpretations of results
  • Demonstrated expertise critically applying machine learning to computational biology, including scientific publications at high-impact journals and/or top conferences in the field
  • Deep experience in Python/R
  • Comfortable working in cloud computing environments and with version control systems
  • Experience working in cross-functional environments and influencing the decision making of senior/executive stakeholders
  • Capable of engaging both technical and non-technical stakeholders
  • Adept at crafting compelling presentations and scientific narratives for high-level stakeholders and internal teams

Nice to have:

  • Translational Oncology/Immunology Research: Demonstrated experience leading computational biology efforts in translational research from IND filing to clinical trials
  • Single Cell & Spatial Expertise: Extensive experience in computational biology research, in particular in single cell and spatial domains, applying AI/ML models in translational or clinical research
  • Project Leadership Experience: Demonstrated ability to manage complex projects, and deliver results in a fast-paced environment
  • Internal/External Leadership: A track record of impactful contributions to computational biology, drug discovery & development, or foundation models. Demonstrated success mentoring junior scientists
  • Entrepreneurial Mindset: Experience in a startup or innovative environment, showing adaptability, proactiveness, and eagerness to take on varied responsibilities
  • Stakeholder Management: Proven success in matrixed or consulting activities, shaping product offerings, and ensuring stakeholder satisfaction through ongoing relationship management
What we offer:
  • Globally competitive salary and equity package
  • Flexible work arrangements, including remote options
  • Opportunities for professional growth and leadership development

Additional Information:

Job Posted:
December 06, 2025

Employment Type:
Fulltime
Work Type:
On-site work
Icon
Bioptimus - All Job Offers
Job Link Share:
Copy Link Icon
Facebook Icon Twitter Icon LinkedIn Icon

Looking for more opportunities? Search for other job offers that match your skills and interests.

Briefcase Icon

Similar Jobs for Computational Biology Lead

Scientific Coding Research Specialist

We are hiring highly analytical and computationally proficient researchers acros...
Location
Location
India , Noida
Salary
Salary:
Not provided
aqusag.com Logo
AquSag Technologies
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • PhD or PhD candidate in Computational Physics
  • At least one peer-reviewed publication
  • Advanced proficiency in Python for scientific coding
  • PhD or PhD candidate in Computational Biology or Bioinformatics
  • At least one peer-reviewed publication
  • Advanced Python skills for modelling or biological computation
  • PhD or PhD candidate in Computational Mathematics
  • At least one peer-reviewed publication
  • Advanced Python skills for numerical methods or algorithmic computation
  • PhD or PhD candidate in Computational Chemistry
Job Responsibility
Job Responsibility
  • Develop original, research-grade or graduate-level scientific problems in your domain
  • Use Python for scientific coding, modelling, simulation or analytical computation
  • Define problem categories, secondary tags and difficulty levels clearly
  • Solve all formulated problems rigorously, ensuring methodological precision, reliability and coherent reasoning
  • Participate in two-tier review cycles to evaluate accuracy of problems and solutions
  • Review peer submissions with a focus on scientific correctness and internal consistency
  • Incorporate feedback promptly and refine content to maintain high quality standards
  • Work closely with reviewers and team leads to uphold overall technical excellence
Read More
Arrow Right

Postdoctoral Fellowship in AI for Biology

The Tang Lab develops explainable, autonomous, and multimodal artificial intelli...
Location
Location
Canada , Vancouver
Salary
Salary:
55000.00 - 70000.00 CAD / Year
jobrxiv.org Logo
jobRxiv
Expiration Date
February 15, 2026
Flip Icon
Requirements
Requirements
  • Ph.D. in Computer Science, Computational Biology, Bioinformatics, Statistics, or a closely related discipline
  • Strong background in machine learning
  • Strong record of research productivity
  • Experience in deep learning, generative models, or probabilistic modeling
  • Proficient in Python and modern machine-learning frameworks (ideally PyTorch)
  • Strong communication skills
  • Ability to independently drive research projects
Job Responsibility
Job Responsibility
  • Develop next-generation computational and machine-learning frameworks for single-cell, spatial, and multimodal omics data
  • Focus on multimodal representation learning, uncertainty quantification, and interpretable and biologically plausible modeling
  • Build foundational AI tools for biological discovery in cancer, regenerative medicine, and neuroscience
  • Work closely with experimental collaborators to apply methods to real biological datasets
  • Produce high-impact publications
  • Lead first-author publications
  • Develop an independent research profile
  • Fulltime
Read More
Arrow Right

Lead Bioinformatician

We are seeking a lead bioinformatician to establish robust interpretative framew...
Location
Location
United States
Salary
Salary:
130000.00 - 150000.00 USD / Year
jobrxiv.org Logo
jobRxiv
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • PhD in Bioinformatics, Computational Biology, Systems Biology, or related field
  • In-depth experience with NGS data processing (e.g., RNA-seq, ChIP/CLIP-seq, CRISPR screens, peak calling)
  • Fundamental understanding of mRNA lifecycle and associated experimental assays
  • Mastery of core statistical and ML procedures for normalization, differential analysis, dimensionality reduction, and clustering
  • Knowledge of statistical power analyses for experimental design
  • Strong interdisciplinary communication skills
  • Fluency in Unix and scripting languages (e.g., Python, R)
  • Experience with version-control and writing technical documentation
Job Responsibility
Job Responsibility
  • Plan, develop, and execute reusable pipelines for processing NGS data
  • Benchmark and evaluate alternative data processing procedures
  • Conceptualize, design, and implement a robust interpretation framework
  • Identify and integrate multiomic data to inform data interpretation
  • Generate reports/dashboards for data QC metrics and interpretive readouts
  • Collaborate with experimentalists on experimental design and protocol optimization
  • Communicate results (oral, written) to colleagues, collaborators, and stakeholders
  • Manage and advise junior associates
  • Maintain knowledge of state-of-the-art methodologies and best practices
  • Fulltime
Read More
Arrow Right

Postdoctoral Fellowship in Computational Neuroscience and Multimodal AI

The Tang Lab develops interpretable and autonomous artificial intelligence (AI) ...
Location
Location
Canada , Vancouver
Salary
Salary:
55000.00 - 70000.00 CAD / Year
jobrxiv.org Logo
jobRxiv
Expiration Date
February 15, 2026
Flip Icon
Requirements
Requirements
  • Ph.D. in Computer Science, Neuroscience, Biomedical Engineering, Applied Mathematics, or a closely related field
  • Strong record of research productivity
  • Experience analyzing at least one major type of neuroscience dataset (e.g., imaging, electrophysiology, or behavioral data)
  • Proficient in Python and modern deep-learning frameworks (ideally PyTorch)
  • Experience in computer vision, multimodal data fusion, self-supervised or generative modeling is highly desirable
  • Familiarity with explainable AI, causal inference, or biologically inspired neural networks
  • Experience collaborating with experimental laboratories
Job Responsibility
Job Responsibility
  • Develop computational and machine-learning frameworks for multimodal neuroscience data
  • Focus on neural data integration, neural circuit modeling, biologically grounded representation learning, and foundation models for neurobiology
  • Work closely with experimental collaborators to connect computational innovations to biological insight
  • Produce high-impact publications in computational neuroscience and AI
  • Lead interdisciplinary projects
  • Develop an independent research profile
  • Fulltime
Read More
Arrow Right

Post Doctoral Fellow

The laboratory of Dr. Sahin in the Department of Biochemistry and Molecular Biol...
Location
Location
United States , Charleston
Salary
Salary:
Not provided
muschealth.org Logo
MUSC Health
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Doctoral degree (Ph.D. or equivalent) awarded within the last 3 years in bioinformatics, genomics, genetics, computational biology, biomedical informatics, computer science, medicine, biostatistics, or related disciplines
  • Experience in data science in cancer biology and/or immunotherapy development
  • Excellent organizational, written, and oral communication skills
Job Responsibility
Job Responsibility
  • Analyze and interpret complex molecular datasets to identify clinically actionable changes
  • Advance the integration of multi-omics and clinical datasets to uncover mechanisms of tumor evolution, therapeutic resistance, and potential biomarkers
  • Assess molecular biomarkers for inclusion in controlled clinical trials
  • Collaborate with leading scientists to develop innovative workflows and pipelines for high-dimensional data analysis
  • Work with the PI to develop a career development plan and participate in various career advancement opportunities
  • Interact and coordinate efforts with undergraduate/graduate students and postdoctoral fellows in the same research group
  • Stay updated on the latest advancements in bioinformatics and genomics research and present findings to internal teams and external stakeholders, while also publishing research outcomes and presenting at conferences
  • Fulltime
Read More
Arrow Right

R&D Director

Flen Health is looking for a dynamic and visionary R&D Director who combines str...
Location
Location
Belgium , Kontich
Salary
Salary:
Not provided
flenhealth.com Logo
Flen Health GmbH
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Ph.D. in biopharmaceutical sciences, molecular biology, or a related discipline
  • Extensive experience in biopharmaceutical R&D, with a strong track record in wound healing and dermatology
  • Demonstrated hands-on expertise in functional genomics, structural and molecular biology, computational methods, and advanced skin and wound modelling
  • Proven success in leading and actively participating in teams and complex research projects
  • Strong publication and patent record in peer-reviewed journals, with direct contributions to scientific literature
  • Experience in securing and managing national and international research grants, including hands-on grant writing and project execution
  • Proven ability to lead international research consortia, delivering impactful outcomes through both strategic oversight and direct scientific involvement
  • Background in topical product development, with practical experience in formulation and testing
Job Responsibility
Job Responsibility
  • Provide both strategic direction and active, hands-on leadership to the R&D team, personally engaging in critical research activities and mentoring scientists at all levels
  • Lead by example in the discovery and development of new biopharmaceutical compounds, directly contributing expertise to projects targeting wound healing and skin inflammation
  • Build and strengthen the scientific evidence base for existing medical device products through direct involvement in experimental design, data analysis, and publication
  • Integrate disease insights with advanced pre-clinical methodologies, including functional genomics, structural and molecular biology, computational approaches, and both in vitro and in silico skin and wound models- by actively participating in experimental work and troubleshooting
  • Foster a culture of collaboration, innovation, and continuous improvement within the team by working side-by-side with team members and encouraging open scientific dialogue
  • Maintain a relentless focus on delivering value to patients and healthcare professionals ensuring that leadership decisions are grounded in practical, real-world impact
  • Establish and expand national and international research networks, leading projects and consortia that result in commercially viable innovative patents and products, including those supported by scientific grant programs
What we offer
What we offer
  • Excellent working conditions
  • An innovative and inspiring work environment
  • Independent project work & responsibilities within a professional team
  • Career prospect
  • Learning and development opportunities
  • Flexible working ecosystem
  • Enthusiastic colleagues
  • Attractive remuneration package
  • Fulltime
Read More
Arrow Right

Senior / Principal Machine Learning Scientist

Our mission is to restore cell health and resilience through cell rejuvenation t...
Location
Location
United Kingdom , Cambridge
Salary
Salary:
136000.00 - 261050.00 GBP / Year
altoslabs.com Logo
Altos Labs
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Ph.D. in Machine Learning, Computer Science, Artificial Intelligence, Statistics, or a related quantitative field
  • 6+ years of relevant post-PhD work experience in either an academic or industry setting
  • Proven experience developing and applying complex machine learning models
  • A strong track record of leading and publishing innovative, peer-reviewed research in top-tier ML conferences or high-impact scientific journals
  • Excellent scientific communication skills
  • Expertise in several of the following: deep learning, reinforcement learning, generative models, language models, computer vision, Bayesian inference, causal reasoning & inference, transfer & multi-task learning, graph neural networks, active learning, hybrid mechanistic/ML models
  • Proven experience applying sophisticated ML techniques to molecular and cell biological data sets
Job Responsibility
Job Responsibility
  • Pioneer novel machine learning methodologies and statistical frameworks
  • Contribute to setting the long-term technical vision and research strategy for a core domain within the Institute of Computation
  • Translate your deep understanding of the mathematical and theoretical underpinnings of cutting-edge AI research into high-impact applications
  • Design, implement, and optimize large-scale machine learning systems using modern frameworks and agile practices
  • Develop and manage efficient distributed training strategies across multiple GPUs and compute clusters
  • Develop robust approaches for multi-modal data integration and cross-domain mapping to extract actionable biological insights
  • Apply computational thinking to solve problems in drug target identification, compound assessment, and prediction of cellular perturbation responses
  • Lead the full ML development lifecycle from theoretical conception and data strategy through model development, training, and evaluation
  • Act as a key technical mentor to Machine Learning Scientists and Engineers
  • Fulltime
Read More
Arrow Right
New

Bioinformatics Scientist

Research Computing supports basic, translational, and clinical research by provi...
Location
Location
United States , Boston
Salary
Salary:
78540.80 - 125652.80 USD / Year
childrenshospital.org Logo
Boston Children's Hospital
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Bachelor’s degree in science, technology, engineering or mathematics
  • Ph.D. in Bioinformatics, Computational Biology or related preferred
  • Minimum of one year of advanced bioinformatics experience
  • Extensive knowledge of the use of open-source bioinformatics software and pipelines in high-performance computing (HPC) environments
Job Responsibility
Job Responsibility
  • Providing computational support by applying a wide range of bioinformatics tools and technologies
  • With supervision and direction, completing assignments in the required timeframe while consistently adhering to standard operating procedures and best practices
  • adapting to a changing environment, resolving problems associated with assignments and seeking supervisor assistance when needed
  • Routinely co-leading or participating in research computing projects with other members from the BCH research community
  • setting goals and objectives for projects and demonstrating achievement of those goals and objectives
  • coordinating work activities with other stakeholders
  • contributing to the resulting presentations and/or publications
  • Training staff and researchers
  • effectively tailoring presentations
  • Communicating scientific findings clearly through presentations, email, memos, and scientific publications
What we offer
What we offer
  • flexible schedules
  • affordable health, vision and dental insurance
  • child care and student loan subsidies
  • generous levels of time off
  • 403(b) Retirement Savings plan
  • Pension
  • Tuition and certain License and Certification Reimbursement
  • cell phone plan discounts
  • discounted rates on T-passes
  • Fulltime
Read More
Arrow Right
Jobs by Category
Art and Entertainment Jobs Banking Jobs Call Center Jobs Construction Jobs Consulting Jobs Customer Service Jobs Education Jobs Energy Jobs Finance Jobs Gastronomy Jobs Health and Beauty Jobs Hospitality and Tourism Jobs Human Resources Jobs Insurance Jobs IT - Administration Jobs IT - Software Development Jobs Legal Jobs Logistics Jobs Manufacturing Jobs Marketing, Digital Marketing, SEO, SEM Jobs Media Jobs Nursing Jobs Office Administration Jobs Pharmacy Jobs Physical Work Jobs Public Relations Jobs Public Sector Jobs Purchasing Jobs Quality Control Jobs Real Estate Jobs Research and Development Jobs Sales Jobs
Job Positions Jobs by Country
United States Jobs United Kingdom Jobs India Jobs Canada Jobs Australia Jobs Germany Jobs Ireland Jobs Poland Jobs
Company
Blog About Us Contact
Follow Us
Facebook
X (Twitter)
LinkedIn
Instagram
CrawlJobs Group
ITFlashcards AllDevBlogs
© 2026 CrawlJobs Ltd. All Rights Reserved
Terms & Conditions Privacy Policy